The Powerpoint presentations that I use in class are
uploaded each afternoon after class. Sometimes I forget. If
you need to access a presentation, and I have not posted it yet, please
email me.
Depending on
your browser, you may view them on-line or download them and view them
using Powerpoint. Please keep in mind that these figures act as a
jumping off point for teaching and discussing in class, and there may
be information that was discussed in class that did not have an
accompanying figure. Click on the dates to access the
presentation.
8/29 Class Introduction and How do
we answer scientific questions?
8/31 Strong Inference (article as pdf)
9/5 DNA Structure and Gene
Perspectives
9/7 DNA Perspectives and
Transposons
9/10 The RNA World
Hypothesis and an Introduction to Signal Transduction
9/12 Signal
Transduction: Why So Many Steps?
9/14 How does calcium play
such a ubiquitous and diverse role in signal transduction?
We will look at figure 1 from Scrase-Field and Knight,
Current Opinion in Plant Biology 2003, 6:500–506;
figures 1and 2 from Allen et al., Nature, Vol 411:1053-1057, 28
June 2001; and figure 3 from Shaw and Long, Plant Physiology,
March 2003, Vol. 131, pp. 976–984
These articles can be found at http://www.lib.utexas.edu:9003/sfx_local/azlist
by entering the journal title and then looking for the appropriate
volume.
9/17 The End of
Calcium and the Direction of Transcription
9/19 Transcription and RNA
Processing
9/21 Translation and Nature
and Nurture
9/24 More Nature and Nurture
mini-quiz
over Nature/Nurture (now with answers)
End of Material for Exam 1
9/28 Introduction to Regulation
of Gene Expression and Arrest of Transcription after DNA Damage
(see article: Kruhlak M. et al
in Nature Vol 447 pg 730-734 (7 June 2007))
10/1 Regulation of Gene
Expression in Bacteria (Noon class, the lectures are
presented as originally intended with the article about rRNA
transcription inhibition by DNA damage on Friday 9/28.)
10/3 Regulation of Gene
Expression at the level of DNA
Article: Four
Stranded DNA (pdf)
10/5
Regulation of Gene
Expression: Transcription and RNA Processing (see article:
Mammalian mRNA
Splice-Isoform Selection Is Tightly Controlled by Jennifer L. Chisa and
David T. Burke in Genetics, Vol.
175: 1079-1087, March 2007)
10/8 Regulation of Gene
Expression: RNA Transport, RNA Degradation, and Micro/Silencing
RNA
10/10 Regulation of Gene
Expression: Translation and Post-translation plus
Development: Exposure to Smoke
During Development: Fetal
Programming of Adult Disease (2006) Bergen H., Tobacco Induced
Diseases
3:5-16
10/12 Development
10/15 Development and
Genome Organization
10/17 Genome Organization
including two articles by the same
group: Recently Mobilized
Transposons in the Human and Chimpanzee Genomes (2006)
Ryan E. Mills, E. Andrew Bennett, Rebecca C. Iskow, Christopher T.
Luttig, Circe Tsui, W. Stephen Pittard, and Scott E. Devine The
American Journal of Human Genetics Volume 78 pg 671-679 and
Which transposable elements are active
in the human genome? (2007) Ryan E. Mills, E. Andrew Bennett,
Rebecca C. Iskow, and Scott E. Devine Trends in Genetics Vol.23 No.4 pg
183-191
10/19 Using PCR and RFLPs for
DNA Fingerprinting
10/22 What is being genetically
engineered and why?
10/24 How can DNA from another
organism be inserted into bacteria?
10/26 How are other organisms
genetically modified?
mini quiz over genetic engineering
techniques
mini quiz answers
End of material for Exam #2
11/2 DNA Replication (as pdf)
11/5 Problems during DNA
Replication: Errors and Ends (as pdf)
11/7 Telomeres and
Mitosis
11/9 Mitosis and Cancer
11/12 Cancer Causes and
Treatments
11/14 Cancer Treatments,
Diagnosis by Microarray, and an introduction to Meiosis
11/16 Meiosis, Creating
Genetic Diversity, and Inheritance
11/19 Inheritance:
incomplete dominance, codominance, sex-linked genes
11/26 Inheritance: mtDNA
and linkage mapping
11/28 Inheritance:
linkage mapping of two and three genes, multiple genes for one trait,
and one gene for multiple traits
Quiz for noon class discussion
on 11/30 and 12/3
11/30 Using Probability in
Inheritance and an Introduction to Evolution
12/3 What does DNA tell us
about the origins of humans?
Pre-exam 3 quiz answers
(If you want some practice for solving genetics problems you can look
at the following problems from the textbook: Chapter 2- 1, 4-6,
8, 9, 14, 20, 22, 27-30, 32, 33, 35, 37, 38, 43, 45-47, and 52.
Chapter 3- 1, 2, 9, 14, 17, and 20. Chapter 4- 1-3, 6, 7, 10, 12a
and b, and 14. Chapter 6- 7 and 12)
Answers to book questions as pdf
End of Material for Exam #3